The effect of a single dose of intravenous tranexamic acid on visual clarity in knee arthroscopic meniscectomy without a tourniquet

Background/Aim: Tranexamic acid (TXA) is known to reduce intra-articular bleeding during arthroscopic procedures, which can improve visibility and postoperative pain knee joint swelling from hemarthrosis. However, insufficient data supports the routine use of TXA in meniscectomy. This study aimed evaluate effect a single dose intravenous (IV) on visual clarity meniscectomy without tourniquet.
 Methods: A randomized, double-blind, controlled trial was conducted assess for tourniquet. Between January 2021 February 2022, 53 patients undergoing were randomly assigned either group (n=27), who received 1 g IV-TXA, or control (n=26), 100 ml normal saline. Visual evaluated using Numeric Rating Scale (NRS). Patients also assessed need tourniquet, tourniquet time, total operative volume irrigation fluid, pain, hemarthrosis, function day 3 weeks 1, 2, 4, Lysholm scoring scale.
 Results: There no significant difference intra-operative between groups (P=0.394). Tourniquet required three cases four (P=0.646). two regarding grade motion, Knee Score after operation.
 Conclusion: The administration IV-TXA did not provide any benefits such as enhanced surgical visualization, reduction inflate due obstructed visibility, decrease VAS score, improved range motion period when compared group.